Villa Anna was build in 1901 by pharmacist Frans van der Grinten.
Pharmacist van der Grinten was a very successful businessman and inventor. Around 1901 he invented the butter colouring, he sold this to van den Bergh en Jurgens, the successor of Unilever. They used the butter colouring to colour the margarine. For decades van den Bergh tried to copy the butter colouring, without any success. Eventually Océ van der Grinten sold the recipe for the butter colouring to van den Bergh en Jurgens and decided to focus mainly on copying machines.